Áttörés az Alzheimer-kutatásban - felejtek.hu

Áttörés az Alzheimer-kutatásban

2019.09.02. 11:00

A demenciáról

forrás: hvg.hu

A Kaliforniai Egyetem irvine-i kampuszának biológusai laboratóriumi körülmények között felfedezték, hogyan lehet megelőzni az Alzheimer-kórt, eredményeik a jövőben segíthetnek új gyógyszerek kifejlesztésében - számol be az áttörésről a hvg.hu

A Nature Communications című szaklap aktuális számában azt írták, hogy amikor az Alzheimer-kór rágcsálómodelljeinek eltávolították az agyi immunsejtjeit, a mikrogliákat, nem alakultak ki a kórra jellemző lerakódások, a béta-amiloid plakkok.

"Nem tudtuk pontosan, mit történik a mikrogliákkal, és miért fontosak az Alzheimer-kór kezdeti szakaszában. Ezért döntöttünk úgy, hogy megnézzük, mi történik, ha eltávolítjuk őket" – mondta Kim Green neurobiológus.

A kutató szerint döbbenetes volt felfedezni, hogy azokon a területeken, ahol nincsenek mikrogliák, nem alakulnak ki plakkok. Mindez arra utal, hogy a mikrogliáknak elengedhetetlen szerepük van az Alzheimer-kór kialakulásában.

Mindez pedig reményt jelenthet arra, hogy az Alzheimer-kór kialakulását megelőző gyógyszert fejleszthessenek ki a tudósok.

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