Nem törvényszerű a demencia
Szemlézte: Pöltz Ágnes
2018.12.03. 09:58
Ugyan sokan gondolhatják azt, hogy az időseknél a demencia kialakulása szinte elkerülhetetlen, ám a pittsburghi egyetem kutatói egy olyan újabb kockázati tényezőt azonosítottak, mely még a hajlott korúak esetében is megváltoztatható.
A Journal of Alzheimer’s Disease szaklapban közzétett kutatás során tizenöt éven keresztül vizsgáltak több száz idős résztvevőt. Azt találták, hogy a nagy verőér (aorta) merevsége még az agyi elváltozások kisebb jeleinél is pontosabban előrejelzi azt, hogy kinél fog később demencia kialakulni. Mindez azért lehet jó hír, mert az érfal rugalmassága vérnyomáscsökkentő gyógyszerekkel és életmódbeli változtatásokkal mind javítható, ezért a nagyobb kockázattal szembenéző betegeknél még a demencia kialakulása előtt visszafordítható lehet a károsodás.
A merev aortáról eddig azt gondolták, hogy azzal járulnak hozzá a demenciához, hogy a verőér falának alacsony rugalmassága kevésbé képes tompítani a szívből az agy felé áramló vér lüktetését, emiatt pedig az agyat is károsodások érhetik. A sok kisebb agyi sérülés pedig úgynevezett „néma” agykárosodáshoz és szellemi hanyatláshoz vezethet. A vizsgálat ugyanakkor arra mutatott rá, hogy nem csak közvetetten, hanem a fenti folyamattól függetlenül is növeli a demencia kialakulásának kockázatát, ha egy beteg aortájának fala merevvé válik.
Mindez azért kiemelkedő gyakorlati jelentőségű, mert azzal szemben, hogy a már kialakult agyi károsodások visszafordítása érdekében semmit nem tehetünk, az időben felismert érrendszeri elváltozások sikeresen és hatékonyan kezelhetők. A korai szűréssel tehát akár még a tünetek megjelenése előtt felvehetjük a harcot a demencia ellen.
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